Conference
Mo – Mi | 18. – 20.09.2023
From Concepts to Clinic: a New Era of Nucleic Acid Therapeutics
Nucleic acid-based compounds are highly target-specific and, compared to other classes of therapeutics, relatively simple to manufacture for therapeutic purposes. It is now the time to overcome the last hurdles towards the widespread application of this therapeutic opportunity in a growing number of diseases. This goal requires an in-depth understanding of the chemical, biological and clinical challenges in the field.
Bernhard Schermer
@cilib
Thrilling times!
Following the exhilarating pre-kickoff rendezvous with #Theracil in Paris, today marked the electrifying pre-kickoff of Workpackage 2 in Cologne
Our marathon discussions have truly borne fruit, propelling us forward with absolute clarity!
A huge thanks to everyone who journeyed to Cologne or powered up zoom to join us!
Ready, set, let the journey commence!!! 🚀🎉
#TheraCil #Ciliopathy #RareDisease #Collaboration #Science #Cilia #Sciencemastodon
📣 Paper Alert! Just Published: Exciting news!
Our Hippo Team's latest study on Nucleoporins (NUPs) and their impact on the localization and activity of YAP/TAZ in podocytes: Another piece of evidence highlighting the significance of YAP/TAZ in FSGS!
A big thank you to the entire team for this fantastic collaborative work!
Heute sind wir zum ersten Mal mit einem eigenen Wagen Teil der #CSD-Parade in #Köln. Rund 300 Beschäftigte der #Uniklinik #Köln setzen beim #ColognePride unter dem Motto „Vielfalt ist die beste Medizin!“ ein Zeichen für Menschenrechte und gegen Diskriminierung.
#happypride
SYMPOSIUM - am 12.08 findet das 6. Kölner Symposium der Altersmedizin statt. Wir freuen uns auf ein abwechslungsreiches Programm rundum die neuesten Entwicklungen und Therapien in diesem Bereich.
Die Teilnahme ist kostenlos, wir bitten aber freundlich um Anmeldung unter nephrologie@uk-koeln.de. Weitere Infos und Programm: https://lnkd.in/ez-3BgCA
#altersmedizin #uniklinik #nephrologie #symposium #geriatrie #frailty #kardiologie #gesundesaltern
MEDIENTIPP - Organspende von und für ältere Menschen. Darüber spricht Prof. Dr. Christine Kurschat der Klinik II für Innere Medizin in der WDR Lokalzeit.
Zum Gespräch geht es hier https://lnkd.in/e4RsKGAf
#nephrologie #organspende #senioren #spenderorganen #transplantation #wdr
Vor einigen Monaten fand das PKD Abendsymposium der Uniklinik Köln in Zusammenarbeit mit dem Verein PKD Familiäre Zystennieren e.V statt. Unter folgendem Link können Sie alle Vorträge nochmal nachhören.
https://lnkd.in/ewhwVaQc
#ADPKD #Symposium #Nephrologie #Nierenerkrankung #Zystennieren
We are very happy that out latest paper about BTLA in glomerulonephritis was just published online at JASN. Congrats to the whole BTLA team!
https://lnkd.in/gU22DSSY
And so it goes ! 😊
Wonderful to see this ! 😊
#Cilia2024 is the new #Cilia2022 !
Thanks so much to Oliver Blacque and team!
#Ciliopathies #ADPKD #BBS #NPHP #RareDiseases #PCD
#Flagella #CellSignaling #DevelopmentalBiology #Conference
📣 Today the very last invoice of "EMBO Cilia2022" was finally transferred and so this chapter closes.
A final huge THANK YOU to ALL who made this meeting such a success!
Looking forward to meeting you in Dublin at Cilia2024 🙂🙂🙂
#Cilia2022 #Cilia2024 #EMBOCilia2022 #Ciliopathy #RareDisease
Uniklinik Köln Universität zu Köln Intercom Dresden #thankyou
https://portal.uni-koeln.de/en/universitaet/aktuell/press-releases/single-news/new-dfg-research-group-investigates-causes-and-consequences-of-genome-instability
focussing on the (patho)physiological consequences of genome instability led by Bjoern Schumacher @schumacherbj and Stephanie Panier.
🧬 A new consortium in
🙏 A huge THANK YOU to Bjoern, Steffi, and everyone else in the enterprise!
Stability is what we need 😉
@CECAD @MPIAGE @UniKoeln
#DFG #FOR5504 #UniklinikKöln
Bernhard Schermer
- within the framework and with the support of the @SFB1403 
@cilib
📣 📣 Happy to share our 1st paper on cilia & cell death
👉 https://www.nature.com/articles/s41420-022-01272-2
Excellent work, primarily by Emilia, who has killed billions of cultured cells along the way 😉
1000x🙏 to Emilia and the team🥳 🎉!
Right now, we study this in preclinical models to check for translational potential. So more in vivo data will follow soon!
#cilia #CellDeath @cilia #necroptosis #UniklinikKöln @CECAD @UniKoeln
"
Herzlich Willkommen,. PKD e.V. !
Toll, dass Sie jetzt auch auf Mastodon sind! 🙂
Es ist unsere große Sorge, dass mit Twitter ein wichtiger Link zwischen Patient:innen und Wissenschaftler:innen wegbrechen könnte und die Alternative nur langsam in Gang kommt. Daher ist es super, dass PKD e.V. hier an Bord ist! 🙂
@cilia @nephrology
#Cilia #Ciliopathies #raredisease #ADPKD #Nephrology #Nephrologie #NeuHier #Medicine #Medizin
Es war ein schöner und sehr interessanter gemeinsamer Abend. Vielen Dank @PKD_eV für die gemeinsame Organisation @UKKoeln https://t.co/IzPSpabIW2
RESET-PKD: A pilot trial on short-term ketogenic interventions in ADPKD https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfac311/6845752#.Y4NdRb51DwA.twitter RESET-PKD was a great team effort
But it is important to understand what the results of this study mean. Let me share my thoughts below. #kidney #keto
Focussed on #nephrology or #cilia / #ciliopathies?
Two helpful groups on #ScienceMastodon🐘
https://a.gup.pe/u/cilia
https://a.gup.pe/u/nephrology
Once you follow a group and mention the group in a post, this will be shared with the entire group. A fast track to being found & connect
Handing over the baton! 😀 🇮🇪 😀
@EuroCilia2022 #cilia2022 #cilia2024
https://t.co/x4RFAJJWtl
CONGRATULATIONS !!! 🥳🎉👏🥳🎉👏🥳🎉
#cilia2022 @EuroCilia2022 @EMBO @UKKoeln
https://t.co/HKkQPNumrs
🙂What a fantastic community!!! 🙂 Cilia enthusiast at EMBO Cilia2022 & Cilia2022-Interconnect
@EuroCilia2022 #cilia2022 @EMBO @EJPRareDiseases
Picture: MedizinFotoKöln D.Hensen
@UKKoeln https://t.co/hdUkdd6U4O
„I‘m not the smartest fellow in the world, but I can sure pick smart colleagues.“
Franklin D. Roosevelt
🙏🙂
#cilia2022 @EuroCilia2022
Picture: MedizinFotoKöln D.Hensen @UKKoeln
https://t.co/kxPqCUAXHq
I totally forgot to mention this, sorry, sorry, sorry!
Many thanks to the nursery team of @UniCologne 🙏🙂🙏🙂
This was probably one of the first cilia meetings with onsite child care!
#cilia2022 @EuroCilia2022
Picture: MedizinFotoKöln D.Hensen @UKKoeln https://t.co/zNeL52XWv1
Cilia and death🏜, hmmm , cell death 😉 Latest data of Emilia from our Nephrolab! Great presentation! Part of our project within @sfb_1403 #cilia2022
@EuroCilia2022
https://t.co/PZRynJYMcQ
Day 3 is about to start! Thanks for being with us @EuroCilia2022 #cilia2022 @embo
Picture: MedizinFotoKöln D.Hensen @UKKoeln https://t.co/jcPhDeLKwZ
🙏🙏🙏 Very special thanks and warmest greetings to our 3 colleagues, whose self-testing was positive this morning and who are now following @EuroCilia2022 online from their hotels. YOU ARE OUR HEROES! 🦸♀️🦸♂️ We can't thank you enough for acting so responsibly!!! #cilia2022
Networking from its finest -
Cilia2022-Interconnect
#Cilia2022 @EuroCilia2022
https://t.co/xA0DaNIwTq
🎉🎉 Congratulations to @DrSueMcGlashan and James Williams for winning the poster prizes of the patients‘ poster session
@EuroCilia2022 (with a Cologne cosy dome / ‚Kuscheldom‘ 🙂)
👍 Master cilia communicators 2022! #cilia2022
https://t.co/c8hQjoCvZm
Raising awareness of Bardet-Biedl syndrome (BBS) and raising funds for BBS-UK.
It was my great pleasure to accompany this power team yesterday on their second day from Bonn to Eindhoven. The Cilia Cyclists are cycling the complete distance from Mainz to Northhampton (~675 km !) where the BBS UK Annual Conference will start on Sept 10.
If you want to find out more and support them, here is the webpage:
https://lnkd.in/ekG9-3zp
The BBS UK Annual Conference is a live-streamed event: https://lnkd.in/eqa_NMMm
#cilia #ciliopathies #BBS #ciliacylists #team #power
📣📣📣 The program of the @EMBO workshop @EuroCilia2022 (October 4-7, 2022, Cologne) is now almost finalized and available on our webpage 🙂 https://t.co/6ylktO7pSm Registration is still open ... #cilia #ciliopathy @UKKoeln @CECAD_ @UniCologne https://t.co/K6091Zxqzs
ADPKD - Roman-Ulrich Müller im Gespräch mit Prof. Dr. Gunnar Heine, Dr. Insa Emrich und Andreas Kronbichler zu Diagnose und Therapiestandards der ADPKD.
https://lnkd.in/es677ySk
#nephrologie #selteneerkrankungen #adpkd #uniklinik #koeln #therapien #aki #zystennieren #clinicaltrials
RT @MuellerRom: Great News! #Diet in #ADPKD. KETO-ADPKD trial completed. Some obstacles...but the motivation of the patients + team @UKKoel…
📢📢📢Latest news from the @EMBO workshop EMBO Cilia2022 @EuroCilia2022 Keynote lectures by 🌟 Phil Beales @PhilBeales (Oct 4) & 🌟 Tim Stearns @StearnsLab (Oct 7) 🥪🥨 Lunch seminars by editors of EMBO press and by @My_Green_Lab more info soon @ https://t.co/zBMnpN0cBz https://t.co/Bq8KYDk1cQ
☀️🚲📷🙂 Beyond cilia and flagella, there are many great reasons to visit Cologne. We snapped a few of them this sunny summer weekend. Only about ten weeks until the start of the @EMBO workshop EMBO Cilia2022 @EuroCilia2022 !!! #cilia #ciliopathies https://t.co/EmYBa2G6w4
The final version of our study on eicosanoids in CR-induced nephroprotection and AKI is now out in Kidney International. Since my university does not provide access (and I assume others may neither) let me share the unrestricted link below https://t.co/5jPL6lwvc5 #kidney #diet
📢 Cilia2022 - Interconnect 🙂
We are thrilled to announce that, in line with the EMBO workshop EMBO Cilia2022", the network event “Cilia2022 Interconnect” will take place - thanks to the generous support of the European Joint Programme on Rare Diseases (EJP RD)🙏!
With Cilia2022-Interconnect, we aim to expand the #cilia & #ciliopathy community to countries typically underrepresented in patients‘, clinical and research networks.
Cilia2022-Interconnect includes >20 stipends for ciliopathy patients, clinicians, and scientists to attend both Cilia2022-Interconnect & EMBO Cilia2022 in Cologne (Oct 4-7, 2022).
Please share this with ciliopathy patient organizations, clinicians, and researchers in the following countries:
Armenia, Bulgaria, Croatia, Czech Republic, Estonia, Georgia, Hungary, Latvia, Lithuania, Malta, Poland, Romania, Serbia, Slovakia, Slovenia, and Turkey.
More details at:
https://lnkd.in/evauPGYh
#research #event #network #cilia2022 #cilia Uniklinik Köln CECAD Cologne Universität zu Köln"
Congratulations to @LiobaEster for a brilliant thesis defense @CECAD_ @UKKoeln 🎉🥳🍾 !!! Many thanks to Joseph Bonventre and his team for allowing Lioba to enter the world of kidney organoids! https://t.co/QLX2BC0UIe
PUBLICATION - one of our latest projects within the research unit deals with the problem of structural variant detection in complex loci like the CFH gene cluster.
We present a comprehensive and complementary approach that can be useful to identify SVs causing aHUS and related disorders.
Many thanks to Nikolai Tschernoster, Janine Altmüller and the entire team.
Link to article: https://lnkd.in/eydu4xCr
#kidneydisease #nephrolab #genecluster #uremic #ckd #köln #clinicalresearch #renalresearch #complementsystem
Wir suchen - Labortechnische/n Assistenten/Assistentin (MTA/BTA) (w/m/d) für das Studienzentrum der Klinik II für Innere Medizin der Uniklinik Köln. Unser Fokus liegt auf der Planung und Durchführung wissenschaftsgetriebener Interventionsstudien, sowie multizentrischen Registerstudien bei denen eine enge Zusammenarbeit mit unserem grundlagenwissenschaftlichen Labor besteht.
Mehr Infos unter: https://lnkd.in/e5iX_fQg
#wearehiring #stellenanzeige #jobsuche #uniklinik #köln #studienzentrum #mta #bta #gesundheitswesen #joboffers #jobs #jobbörse
SYMPOSIUM - online Fortbildungsveranstaltung „Nephrologie trifft Rheumatologie“ der Uniklinik Köln am Samstag, dem 26.03.2022.
Weitere Informationen und Anmeldung: https://lnkd.in/e3JZK49i
#nephrologie #symposium #rheumatologie #uniklinik #koeln #lineupr #virtuell #fortbildung #medizin #webinar
One more step towards understanding #ketogenic diets in polycystic #kidney disease (#ADPKD). The KETO-ADPKD trial has reached its recruitment target of 63 patients today. Thanks to all colleagues @UKKoeln @CECAD_ @UniCologne, @weimbslab, esp. to all patients and @PKDFoundation https://t.co/EamycyG2Qa
Es ist nie zu spät für ein last-minute Weihnachtsgeschenk (auch als ebook) und es ist nie zu früh, über die Zukunft nachzudenken ...
Toller Ratgeber von Cristina Polidori und Anna Meyer aus der Klinik II für Innere Medizin zum Thema 'Altern'.
Uniklinik Köln CECAD Cologne Universität zu Köln
Bernhard Schermer (@BernhardScherm1):
Our new webpage is online bringing together the Nephrolab Cologne, CRU329, AD(H)PKD, Sybacol & REN🥳 Projects of @MuellerRom @HoehneMartin @LinusAlexanderV @HenningHagmann ... Microsc.💪by @SisaLeufert @phillipowers @amer_rc @unnersjo @juLie77677024 ... kidneyresearch.de
Bernhard Schermer (@BernhardScherm1):
Boostern läuft @CECAD_ @UKKoeln 😀💪 1000 Dank an die Kolleg:innen der Klinik II und das ‚CECAD-Impfoffice‘ 🙏👍 #corona #booster
New publication on research into diseases of the #kidney filter. CALINCA - A Novel Pipeline for the Identification of IncRNAs in #Podocyte Disease."
#CECAD #rnaseq #kidneyresearch #nephrolab #clinicalresearch #fsgs #medicalresearch #openaccess #mdpi"
News from the CRU329:
Disease pathways in podocyte injury - from molecular mechanisms to individualized treatment options" at the University Hospital Cologne.
After three successful years, the CRU329 has been approved for renewed funding by the Deutsche Forschungsgemeinschaft (DFG) - German Research Foundation - and is soon entering the next funding period.
Spearheaded by Thomas Benzing and Paul Brinkkötter, members of the research group are working towards deciphering the mechanisms of podocyte disease and developing individualized treatment approaches.
More information can be found at https://www.podocyte.org/, soon to be updated with detailed info on new projects.
#podocyte #nephrolab #fsgs #clinicalresearch #kidneydisease #cecad #uniklinik #UoC"
#RNA Mechanism & Therapeutics in Metabolism Diseases was an amazing experience! Thanks to the Danish Diabetes Academy for organising this great event, giving me the opportunity to present my work and for a poster prize ☺️ See you next time!
#MetRNA2021 #DanishDiabetesAcademy #DDA_education
JASN_News (@JASN_News) RT: @linusbutt:
Mice carrying a common mutation in the gene encoding podicin show signs of podocyte injury as they age and after injection with a nephrotoxin—suggesting that the mutation confers a genetic predisposition to glomerular disease bit.ly/j202006085 @HoehneMartin
Bernhard Schermer (@BernhardScherm1):
Habe kürzlich den wohl ersten überdachten Fahrradständer auf dem Campus der @UKKoeln entdeckt! Yippie! 😀 Vielleicht können ein paar likes❤️ oder retweets bewirken, dass über Nacht weitere vom Himmel fallen und an der Uniklinik und am @CECAD_ keine Räder mehr im Regen stehen ...
Linus Butt (@LinusButt):
Huge thank you to @unnersjo and his microscopy skills for taking us to the cover of @NatMetabolism! @MartinHhne1 @mrins01 @BernhardScherm1 @juLie77677024 @ThomasB93759895 @UKKoeln
scilifelab (@scilifelab) RT: @linusbutt:
An international team of researchers, enabled by the @ALMScilife facility, explores the elusive kidney filtration mechanism, published in @NatMetabolism. ”We take the Nobel awarded STED imaging technique into pre-clinical research for the first time”: bit.ly/2A0q4Hj
David Unnersjö-Jess (@unnersjo) RT: @linusbutt:
Podocytes 🥰. AcTubulin (primary foot processes) in magenta, nephrin (secondary foot processes) in green. Acquired with an SP8 confocal (!) microscope. @LeicaMicro
Bernhard Schermer (@BernhardScherm1) RT: @linusbutt:
#PLOSONE: Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay dx.plos.org/10.1371/journa… Online since 45 min – about the time it takes to detect #SARS_COV_2 with a #LAMP reaction. We are working hard to further improve it & make it a #POCT..😷
Exciting news: the AD(H)PKD study has reached an important milestone - more than 1,000 participants! AD(H)PKD aims to characterize polycystic kidney disease and its course after approval of the first targeted therapy in 2015. We would like to thank all centers, colleagues at Universität zu Köln Uniklinik Köln CECAD Cologne, and especially the participating #ADPKD patients for their invaluable contribution. First insights into the results expected in 2022.